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1 article(s) from Klepel, Florian

A dynamic combinatorial library for biomimetic recognition of dipeptides in water

Florian Klepel and
Bart Jan Ravoo

Beilstein J. Org. Chem. 2020, 16, 1588–1595, doi:10.3762/bjoc.16.131

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Scheme 1: a) Building blocks included in this study. b) Antiparallel and parallel constitutional isomers of t...

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Figure 1: HPLC–MS chromatograms of a reference library for all possible tripeptide dimers ([M + H]⁺ ions).

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Figure 2: a) HPLC–MS chromatograms of the dimers (CFC)₂ and templates YY and FF. b) Amplification of the peak...

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Scheme 2: a) Synthesis of the parallel and antiparallel isomers p(CFC)₂ and a(CFC)₂_. b) Templates FF. YY and ...

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Figure 3: ITC of YY (30 mM) to a(CFC)₂ (1.5 mM) in phosphate buffer (pH 7.4, 100 mM).

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Figure 4: Continuously varied NMR measurements of a) p(CFC)₂ to YY b) p(CFC)₂ to FF c) a(CFC)₂ to YY d) a(CFC)...

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Figure 5: Job plots derived from the continuously varied NMR measurements of a) p(CFC)₂ to YY b) p(CFC)₂ to FF...

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Published 02 Jul 2020

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